New England Surgical Society (NESS)
Search NESS
  Home
  Annual Meeting
  Annual Resident and Fellow Research Day
  Members
      Member Directory
      Members Only
  Scholars Foundation
  Job Board
  Awards
  Journal of the American College of Surgeons
  Newsletters
  Committees
  Contact NESS

Back to NESS Scientific Program


Vascular Assessment in Chronic Wound Care:
Affect of HBO2T on Forecasting Patient Outcome

George A Perdrizet, Justin Mohr, Patrick Worth, Caesar Anderson, Brian Solomon, Christine Shapter
University of Connecticut/Hartford Hospital, Hartofrd, CT

Objective: To report our experience using non-invasive vascular studies (transcutaneous oxygen tension, TCpO2 and ankle/brachial index, ABI) for clinical decision making and demonstrate how the use of HBO2 may affect standard algorithms currently in place.
Design/setting/Patients: A clinical series, sequential adult patients presenting to a comprehensive wound care clinic, within a tertiary care hospital, for evaluation and treatment of chronic lower extremity wounds during a 3 year period (8/03-8/06). Patients were selected if they had had TCpO2 and/or ABI as part of their evaluation and had at least a 10 week follow-up period. Data was extracted from patients’ clinical records with IRB approval.
Main Outcome Measure: Wound healing rate at 10 weeks relative to results of vascular evaluation (A-adequate/E-equivocal/I-inadequate). A comparison of data sets was performed using the Fisher Exact test for diachotomous data and Student’s t test for continuous data. Statistical significance was reached if p = 0.05.
Results: A total of 122 adult patients (115 TCpO2 and 51 ABI measurements) experienced a 56% healing rate at 10 weeks. Healing rates stratified by TCpO2 (A/E/I) were 80%, 40%, and 40% respectively (p < 0.05 A vs E/I) . Healing rates stratified by ABI (A/E/I) were 80%, 80% and 20% respectively ( p < 0.05 A/E vs I). The subset of patients with “Inadequate” TCpO2 had a 27% healing rate at 10 weeks compared to 50% had they received HBO2T (p < 0.05).
Conclusions: Techniques of vascular assessment provide a fair estimate of patients who are likely to heal (A/E groups). However patients with studies considered to be inadequate to support wound healing may respond favorably to HBO2T.


Back to NESS Scientific Program

Copyright © 2018 New England Surgical Society. All Rights Reserved.
Read Privacy Policy.